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Epigenetic Mechanisms in Cancer provides a comprehensive analysis of epigenetic signatures that govern disease development, progression and metastasis Epigenetic signatures dictating tumor etiologies present an opportunity for biomarker identification which has broad potential for improving diagnosis, prognosis, prediction, and risk assessment This volumes offers a unique evaluation of signature differences in childhood, sex specific and race specific cancers, and in doing so broadly illuminates the scope of epigenetic biomarkers in clinical environments Chapters detail the major epigenetic process in humans consisting of DNA methylation, histone modifications and microRNAs miRNAs involved in the initiation, progression and metastasis of tumors Also delineated are recent technologies such as next generation sequencing that are used to identify epigenetic profiles primarily methylation analysis in samples normal, benign and cancerous and which are highly important to the analysis of epigenetic outcomes.Offers broad coverage that is applicable to audiences in various area of cancer research population studies, diagnostics, prognosis, prediction, therapy, risk, etc.Provides critical review analysis of the topics that will clarify and delineate the potential roles of epigenetic signatures in cancer managementCovers basic, as well as, clinical areas of epigenetic mechanisms in tumorigenesisFeatures contributions by leading experts in the fieldProvides comprehensive coverage of current epigenetic signatures involved in the etiology of various cancers and miRNAs...

Title : Epigenetic Mechanisms in Cancer, Volume 3 (Translational Epigenetics)
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ISBN : 0128095520
Format Type : Hardcover
Language : English
Publisher : Academic Press 1 edition November 21, 2017
Number of Pages : 392 pages
File Size : 683 KB
Status : Available For Download
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